Matrix metalloproteinases, tissue inhibitor of metalloproteinase and transforming growth factor A1 in the remodeling of chronic rhinosinusitis in North China
نویسندگان
چکیده
Results MMP-8,9 were the highest among all above MMPs. MMP-8 of NP tissue was much higher than that of CRS and control tissue (P<0.001). MMP-9 of NP tissue was also significantly higher than that of CRSsNP and control tissue (P<0.05). MMP-7 of NP tissue and CRSsNP were much higher than that of control tissue (P<0.001). MMP2 of CRSsNP tissue was much higher than that of NP and control tissue (P<0.001). TIMP-1,2 were the highest among all the four TIMPs. TIMP-1 of CRSsNP tissue was much higher than that of NP and control tissue (P<0.001 and P<0.05 respectively). TIMP-2 of NP and CRSsNP tissue were much higher than that of control tissue (P<0.01). TIMP-3 of CRSsNP tissue was much higher than that of NP and control tissue (P<0.01 and P<0.05 respectively). There were no significantly difference of TGF-¦Â1 among the three groups.
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